Categories: Cancer, cancer data analysis, cancer genetics, Gene prioritization, graph analysis, kegg, mutation analysis, network analysis, Pathway analysis, signaling, variant analysis

### ZDOG: Zooming in on Dominating Genes with Mutations in Cancer Pathways ZDOG is an app for visualization of the extent to which mutated genes may affect cancer pathways using the dominating tree model. The dominator tree model allows us to examine conveniently the positional importance of a gene in cancer signalling pathways. This tool facilitates the identification of mutated “master” regulators even with low mutation frequency in deregulated signalling pathways. For details and the user manual see: [https://github.com/rudi2013/ZDOG]

Authors:

• Rudi Alberts (National University of Singapore)
• Jinyu Chen (National University of Singapore)
• Louxin Zhang (National University of Singapore)