DvD

(6)
**Drug versus Disease (DvD)** provides a pipeline, available through **R** or **Cytoscape**, for the comparison of drug and disease gene expression profiles from public microarray repositories. Negatively correlated (enriched) profiles can be used to generate hypotheses of drug-repurposing whilst positively correlated (enriched) profiles may be used to infer side-effects of drugs. DvD provides a pipeline for comparing drug and disease signatures with dynamic access to databases Array Express, GEO and data from the Connectivity Map. **Publication** [http://bioinformatics.oxfordjournals.org/content/29/1/132.full.pdf Pacini, C., Iorio, F., Gonçalves, E., Iskar, M., Klabunde, T., Bork, P., & Saez-Rodriguez, J. (2013). DvD: An R/Cytoscape pipeline for drug repurposing using public repositories of gene expression data. Bioinformatics, 29(1), 132–134. doi:10.1093/bioinformatics/bts656]
CYTOSCAPE 2

Version 1.0

Released 7 Nov 2012

Works with Cytoscape 2.8

Download Stats Click here