**CONAN was renamed to SenseNet. The new app page can be found at [https://apps.cytoscape.org/apps/sensenet].**
CONAN (``CONtact Network ANalyzer'') maps structure ensembles of biomolecules to atom interaction networks and provides functions for their analysis and visualization.
Protein structures are frequently analysed to gain insights into the effects of ligand binding, residue mutations or conformational changes. In contrast to isolated structures generated by crystallography or other experimental sources, ensembles obtained from Molecular Dynamics (MD) provide additional information such as lifetimes or conformational correlation, allowing to investigate dynamic properties of biomolecules. In a structure ensemble network, each node represents one or several atoms while edges correspond to the interactions between these atoms (e.g. hydrophobic contacts or hydrogen bonds). Each edge is associated with a 'timeline' which indicates the presence of an interaction for each structure in the ensemble. Analysis functions are provided to extract information from these timelines and map results to network nodes and edges. Finally, CONAN offers comprehensive visualization functions for side-by-side analyses of networks and 3D structures.
